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Review Article| Volume 20, ISSUE 3, P419-433, July 2004

Delirium and sedation

      Critically ill patients nearing the end of life are frequently challenged by issues centered around delirium and sedation. Most often these issues arise in the context of changing goals of therapy from cure to comfort, after some attempts at reversing progressive illness have not been successful, and clinicians, families, and possibly patients are coming to terms with this reality. In this setting delirium is common, often with multifactorial etiologies. Clinicians often struggle to ensure comfort to dying patients while permitting communication between patients and loved ones or caregivers. The common experience of pain in these patients and need to provide adequate analgesia further confounds the desire to facilitate communication for dying patients. This article will discuss delirium and sedation as it applies to dying patients, review available literature in this area, and provide recommendations for effective management strategies.
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