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- Global burden of disease and injury and economic costs attributable to alcohol use and alcohol-use disorders.Lancet. 2009; 373: 2223-2233
- Management of drug and alcohol withdrawal.N Engl J Med. 2003; 348: 1786-1795
- Unhealthy alcohol use.N Engl J Med. 2005; 352: 596-607
- 10th special report to the US Congress on alcohol and health. US Dept of Health & Human Services, 2000
- Updating estimates of the economic costs of alcohol abuse in the United States: estimates, update methods & data.Lewin Group for the National Institute on Alcohol Abuse & Alcoholism, 2000 (Available at:) (Accessed March 29, 2012)
- Alcohol, alcohol abuse and alcohol dependence.(#651) CME Resource, Sacramento (CA)2003
- Alcohol and the emergency service patient.Br Med J. 1980; 281: 638-640
- The course of alcohol withdrawal in a general hospital.QJM. 1997; 90: 253-261
- The incidence of alcohol-related problems and the risk of alcohol withdrawal in a general hospital population.Drug Alcohol Rev. 1995; 14: 49-54
- Alcohol-related admissions to an inner city hospital intensive care unit.Alcohol Alcohol. 1996; 31: 393-396
- Substance abuse related admissions to an adult intensive care unit.Chest. 1993; 103: 21-25
- Alcohol-use disorders in the critically ill patient.Chest. 2010; 138: 994-1003
- Alcohol withdrawal syndromes in the intensive care unit.Crit Care Med. 2010; 38S: S494-S501
- Alcohol abuse in the critically ill patient.Lancet. 2006; 368: 2231-2242
- Critical care aspects of alcohol abuse.South Med J. 2005; 98: 372-381
- Tobacco, alcohol and drug use in a primary care sample: 90-day prevalence and associated factors.J Addict Dis. 1998; 17: 67-81
- Comparative effectiveness and cost of inpatient and outpatient detoxification of patients with mild-to-moderate alcohol withdrawal syndrome.N Engl J Med. 1989; 320: 358-365
- Outpatient alcohol detoxification; implementation efficacy and outcome effectiveness of a model project.Eur Addict Res. 2004; 10: 180-187
- Outpatient alcoholism treatment—24-month outcome and predictors of outcome.Subst Abuse Treat Prev Policy. 2009; 4: 15-23
- Management of moderate and severe alcohol withdrawal syndromes.in: Traub S.J. Grayzel J. UpToDate. UpToDate, Waltham (MA)2011 (Available at:) (Accessed March 29, 2012)
- Marijuana and alcohol use among 1023 trauma patients. A prospective study.Arch Surg. 1988; 123: 733-737
- Therapy of alcohol withdrawal syndrome in intensive care unit patients following trauma: results of prospective randomized trial.Crit Care Med. 1996; 24: 414-422
- Association of alcohol use and other high-risk behaviors among trauma patients.J Trauma. 2001; 50: 13-19
- Review of respiratory complications in alcohol withdrawal syndrome at a public hospital.Crit Care Med. 2008; 36: SA69
- Substance abuse related admissions to an adult intensive care unit.Chest. 1993; 103: 21-25
- Alcohol-associated admissions to an adult intensive care unit: an audit.Eur J Anaesthesiol. 2002; 19: 193-196
- Increased incidence of complications in trauma patients cointoxicated with alcohol and other drugs.J Trauma. 2007; 62: 755-758
- Intercurrent complications in chronic alcoholic men admitted to the intensive care unit following trauma.Intensive Care Med. 1996; 22: 286-293
- Adverse clinical outcomes associated with elevated blood alcohol levels at the time of burn injury.J Burn Care Res. 2008; 29: 784-789
- Influence of alcohol consumption on immunologic status: a review.Eur J Clin Nutr. 2002; 56: S50-S53
- High alcohol intake as a risk and prognostic factor for community acquired pneumonia.Arch Intern Med. 1995; 155: 1649-1654
- Severe community-acquired pneumonia. Risk factors and follow-up epidemiology.Am J Respir Crit Care Med. 1999; 160: 923-929
- The impact of alcohol-related diagnoses on pneumonia outcomes.Arch Intern Med. 1997; 157: 1446-1452
- Clinical risks for development of the acute respiratory distress syndrome.Am J Respir Crit Care Med. 1995; 151: 293-301
- Alcohol, immunosuppression, and the lung.Proc Am Thorac Soc. 2005; 2: 428-432
- Influence of alcohol on antimicrobial immunity.Biomed Pharmacother. 2004; 58: 84-89
- Consequences of alcohol consumption on host defense.Alcohol Alcohol. 1999; 34: 830-841
- Alcohol dependence is independently associated with sepsis, septic shock and hospital mortality among adult intensive care patients.Crit Care Med. 2007; 35: 345-350
- At-risk drinkers are at higher risk to acquire a bacterial infection during an intensive care unit stay than abstinent or moderate drinkers.Crit Care Med. 2008; 36: 1735-1741
- Effect of alcohol on the mobilization of alveolar macrophages.J Lab Clin Med. 1968; 72: 40-51
- Alcohol use disorders increase the risk for mechanical ventilation in medical patients.Alcohol Clin Exp Res. 2007; 31: 1224-1230
- Uncorking the past: the quest for wine, beer and other alcoholic beverages.University of California Press, Berkeley (CA)2009
- A history of the world in six glasses.Walker & Co, New York2005
- When to say when: wine and drunkenness in ancient Rome.([MA dissertation]) University of Missouri, Columbia (MO)2010
- Alcohol and epilepsy.Q J Stud Alcohol. 1941; 11: 1-11
- The genuine works of Hippocrates.William Wood & Co, New York1886
- John of Gaddesden on epilepsy.Ann Med Hist. 1939; 1: 283-307
- Introduction.in: Smyth A. A pleasing sinne: drink and conviviality in 17th century England. Brewer DS, Cambridge (United Kingdom)2004: xviii
- The pub in literature: England's altered state.Manchester University Press, Manchester (United Kingdom)2000
Huss M. Alcoholismus chronicus. Eller chronisk alkoholssjukdom; ett bidrag till dyskrasiernas kännedom. Enligt egen och andras efarenhet. Stockholm (Sweden): Beckman; 1851. p. 1849–51. [in Swedish].
- Tracts on delirium tremens, on peritonitis and some other internal inflammatory affections, and on the gout.James Moyes for Thomas Underwood, London1813
- Remarks on the history and treatment of delirium tremens.Med Commun Mass Med Soc. 1836; 5 (cited by Cutshall BJ. The Saunders-Sutton syndrome: an analysis of delirium tremens. Q J Stud Alcohol 1965;26(3):423–8): 136-194
- Our mutual friend.in: Poole A. Penguin, New York1997
- Alcohol: the world's favorite drug. Thomas Dunne Books, New York2000 (p. 73–92)
- A nation under the influence: America's addiction to alcohol.Pearson Education, Boston2003
- Writing under the influence: alcoholism and the alcoholic perception from Hemingway to Berryman.Palgrave-MacMillan, New York2010
Trotter T. An essay medical, philosophical, and chemical, on drunkenness and its effects on the human body. London; 1988. (Facsimile of the 1804 London edition and based on the thesis presented to Edinburgh University in 1788). Wikipedia, The Free Encyclopedia, Wikimedia Foundation. Accessed March 29, 2012.
- An inquiry into the effects of ardents spirits upon the human body and mind: with an account of the means to preventing, and of the remedies for curing them.Thomas Dobson, Philadelphia1808
- The principles and practice of medicine.D Appleton & Co, New York1895 (p. 1057–71)
- Alcohol intoxication and withdrawal.N Engl J Med. 1976; 294: 757-762
- Hypnotics and sedatives.in: Brunton L.L. Lazo J.S. Parker K.L. Goodman & Gillman's pharmacological basis of therapeutics. 11th edition. McGraw Hill, New York2006: 402 (420–1)
- Trichlorethanol potentiates synaptic transmission mediated by gamma-aminobutyric acidA receptors in hippocampal neurons.J Pharmacol Exp Ther. 1993; 264: 1097-1103
- Treatment of alcoholic intoxication and the withdrawal syndrome.Psychosom Med. 1966; 28: 636-648
- Diazepam and paraldehyde for treatment of severe delirium tremens. A controlled trial.Ann Intern Med. 1975; 82: 175-180
- The management of delirium tremens.Med J Aust. 1975; 1: 15-16
- A comparison of promazine and paraldehyde in 175 cases of alcohol withdrawal.Am J Psychiatry. 1961; 118: 323-327
- The history of barbiturates a century after their clinical introduction.Neuropsychiatr Dis Treat. 2005; 1: 329-343
- A strategy of escalating doses of benzodiazepines and phenobarbital administration reduces the need for mechanical ventilation in delirium tremens.Crit Care Med. 2007; 35: 724-730
- A prospective, randomized trial of phenobarbital versus benzodiazepines for acute alcohol withdrawal.Am J Emerg Med. 2011; 29: 382-385
- Comparative clinical evaluation of chlordiazepoxide and promazine in treatment of alcohol-withdrawal syndrome.Br Med J. 1965; 1: 92-97
- Which drug for alcohol withdrawal?.J Clin Pharmacol. 1972; 12: 429-431
- Treatment of the acute alcohol withdrawal state: a comparison of four drugs.Am J Psychiatry. 1969; 125: 1640-1646
- Diagnosis and therapy of acute withdrawal from alcohol.Curr Psychiatr Ther. 1970; 10: 145-150
- Rational use of psychotropic drugs II. Antianxiety agents.Am J Health Syst Pharm. 1974; 31: 1077-1080
- Randomized clinical trial of atenolol in patients with alcohol withdrawal.N Engl J Med. 1985; 313: 905-909
- Screening for alcohol abuse using CAGE scores and likelihood ratios.Ann Intern Med. 1991; 115: 774-777
- Screening for alcohol abuse using the CAGE questionnaire.Am J Med. 1987; 82: 231-235
- Development of optimal treatment tactics for alcohol withdrawal. I. Assessment and effectiveness of supportive care.J Clin Psychopharmacol. 1981; 1: 382-387
- Assessment of alcohol withdrawal: the revised clinical institute withdrawal assessment for alcohol scale (CIWA-Ar).Br J Addict. 1989; 84: 1353-1357
- A new rating scale for the assessment of the alcohol-withdrawal syndrome (AWS scale).Alcohol Alcohol. 1997; 32: 753-760
- Controlled sedation with alphaxalone-alphadolone.Br Med J. 1974; 2: 656-674
- The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients.Am J Respir Crit Care Med. 2002; 166: 1338-1344
- Assessing sedation during intensive care unit mechanical ventilation with the bispectral index and the sedation-agitation scale.Crit Care Med. 1999; 27: 1499-1504
- Prospective evaluation of the sedation-agitation scale for adult critically ill patients.Crit Care Med. 1999; 27: 1325-1329
- Diagnostic and statistical manual of mental disorders.4th edition (text revision). American Psychiatric Association, Washington, DC2000
- Evaluation of delirium in critically ill patients: validation of the confusion assessment method for the intensive care unit (CAM-ICU).Crit Care Med. 2001; 29: 1370-1379
- The disease concept of alcoholism.Hillhouse, New Haven (CT)1960
- Utilization of acute inpatient services for alcohol detoxification.J Ment Health Adm. 1996; 23: 366-374
- Development of an alcohol withdrawal clinical pathway: an interdisciplinary process.J Nurs Care Qual. 1998; 12: 9-18
- An experimental study of the etiology of “rum fits” and delirium tremens.Q J Stud Alcohol. 1955; 16: 1-33
- The effect of alcohol on the nervous system.Res Publ Assoc Res Nerv Ment Dis. 1953; 32: 526-573
- Arterial noradrenaline levels after ethanol withdrawal.Lancet. 1967; 2: 889
- The effect of ethyl alcohol on the secretion from the adrenal medulla in man.Acta Physiol Scand. 1958; 44: 241-247
- Gamma-aminobutyric acid type A receptors and alcoholism: intoxication, dependence, vulnerability and treatment.Arch Gen Psychiatry. 2006; 63: 957-968
- The interactions of ethanol with the benzodiazepine-GABA receptor-ionophore complex.Pharmacol Biochem Behav. 1983; 18: 15-18
- Chronic ethanol treatment alters brain levels of gamma-aminobutyric acid a receptor subunit mRNAs: relationship to genetic differences in ethanol withdrawal seizure severity.J Neurochem. 1991; 57: 1452-1455
- The role of glutamatergic neurotransmission in the pathophysiology of alcoholism.Annu Rev Med. 1998; 49: 173-184
- N-methyl-D-aspartate 2b receptor subtype (NR2B) promoter methylation in patients during alcohol withdrawal.J Neural Transm. 2009; 116: 615-622
- Upregulation of glutamate receptor subtypes during alcohol withdrawal in rats.Alcohol Alcohol. 2005; 40: 89-95
- Alterations of homocysteine metabolism among alcohol dependent patients—clinical, pathobiochemical and genetic aspects.Curr Drug Abuse Rev. 2008; 1: 47-55
- Urinary norepinephrine and epinephrine excretion in delirium tremens.Arch Gen Psychiatry. 1960; 3: 289-296
- Urinary epinephrine and levarternol excretion during acute sublethal alcohol intoxication in dogs.J Pharmacol Exp Ther. 1957; 121: 313-318
- Catecholamine derived compounds in urine and cerebrospinal fluid from alcoholics during and after long-standing intoxication.Subst Alcohol Actions Misuse. 1981; 2: 63-72
- CSF levels of norepinephrine during alcohol withdrawal.Arch Neurol. 1981; 38: 289-292
- Cerebrospinal fluid 3-methoxy-4-hydroxyphenylglycol and norepinephrine levels in alcohol withdrawal. Correlates with clinical signs.Arch Gen Psychiatry. 1985; 42: 1056-1062
- Clinical conditions and concentrations of MOPEG in the cerebrospinal fluid and urine of male alcoholic patients during withdrawal.Alcohol Clin Exp Res. 1983; 7: 411-415
- Comparative efficacy of propranolol and chlordiazepoxide in alcohol withdrawal.J Stud Alcohol. 1977; 38: 2096-2108
- Alcohol withdrawal: effects of clonidine treatment on sympathetic activity, the renin-aldosterone system and clinical symptoms.Alcohol Clin Exp Res. 1985; 9: 238-243
- Experiencia preliminar del tratamiento con dexmedetomidine del estado confusional e hiperadrenergia en la unidad de cuidados intensivos.Rev Esp Anestesiol Reanim. 2002; 49 ([in Spanish]): 403-406
- Transdermal clonidine versus chlorodiazepoxide in alcohol withdrawal: a randomized controlled clinical trial.South Med J. 1991; 84: 312-321
- Clonidine vs chlordiazepoxide in the management of the acute alcohol withdrawal syndrome.Arch Intern Med. 1987; 147: 1223-1226
- Clonidine in the treatment of alcohol withdrawal in the intensive care unit.Br J Anaesth. 1992; 68: 106-108
- Dexmedetomidine in the treatment of withdrawal syndromes in cardiothoracic surgery patients.J Intensive Care Med. 2005; 20: 118-123
- Dexmedetomidine as an adjuvant in the treatment of alcohol withdrawal delirium: a case report.Gen Hosp Psychiatry. 2006; 28: 362-363
- Pharmacological management of alcohol withdrawal: a meta-analysis and evidence-based practice guideline.JAMA. 1997; 278: 144-151
- Propranolol and chlordiazepoxide effects on cardiac arrhythmias during alcohol withdrawal.Alcohol Clin Exp Res. 1980; 4: 400-405
- Propranolol versus diazepam in the management of the alcohol withdrawal syndrome: double-blind controlled trial.Am J Drug Alcohol Abuse. 1994; 20: 115-124
- Management of alcohol intoxication and withdrawal.in: Ries R.K. Fiellin D.A. Miller S.C. Principles of addiction medicine. 4th edition. Lippincott Williams & Wilkins, Philadelphia2009: 559-572
- Increase of extracellular corticotropin-releasing factor-like immunoreactivity levels in the amygdala of awake rats during restraint stress and ethanol withdrawal as measured by microdialysis.J Neurosci. 1995; 15: 5439-5447
- Microinjection of corticotropin-releasing factor antagonist into the central nucleus of the amygdala reverses anxiogenic-like effects of ethanol withdrawal.Brain Res. 1993; 605: 25-32
- Alcohol and withdrawal: from animal research to clinical issues.Neurosci Behav Rev. 2003; 27: 189-197
- Effect of alcohol withdrawal on blood pressure, plasma rennin activity, aldosterone, cortisol and dopamine beta-hydroxylase.Clin Sci. 1984; 66: 659-663
- Serum cortisol levels in alcoholic and nonalcoholic subjects during experimentally induced ethanol intoxication.Psychosom Med. 1966; 28: 616-626
- Ethanol inhibits NMDA-activated ion current in hippocampal neurons.Science. 1989; 243: 1721-1724
- Regulation of NMDA receptors by alcohol.Prog Drug Res. 2000; 54: 152-189
- Alcohol and glutamate.Alcohol Health Res World. 1997; 2: 120-127
- Role of glutamatergic and GABAergic systems in alcoholism.J Biomed Sci. 2001; 8: 7-19
- The glutamatergic basis of human alcoholism.Am J Psychiatry. 1995; 152: 332-340
- Increased glutamatergic neurotransmission and oxidative stress after alcohol withdrawal.Am J Psychiatry. 1998; 155: 726-732
- Increased agonist and antagonist sensitivity of N-methyl-D-aspartate stimulated calcium flux in cultured neurons following chronic ethanol exposure.Neurosci Lett. 1995; 2002: 214-218
- Renaissance of NMDA receptor antagonists: do they have a role in the pharmacotherapy for alcoholism?.Drugs. 2004; 7: 339-350
- NMDA receptors: role in ethanol withdrawal seizures.Ann N Y Acad Sci. 1992; 654: 52-60
- Ethanol withdrawal seizures and the NMDA receptor complex.Eur J Pharmacol. 1990; 176: 289-296
- Antiglutamatergic strategies for ethanol detoxification: comparison with placebo and diazepam.Alcohol Clin Exp Res. 2007; 31: 604-611
- NMDA receptor antagonism and the ethanol intoxication signal: from alcoholism risk to pharmacotherapy.Ann N Y Acad Sci. 2003; 1003: 176-184
- Plasma homocysteine is a predictor of alcohol withdrawal seizures.Neuroreport. 2000; 11: 2749-2752
- Homocysteine as a neurotoxin in chronic alcoholism.Prog Neuropsychopharmacol Biol Psychiatry. 2004; 28: 453-464
- Effects of alcohol detoxification on dopamine D2 receptors in alcoholics: a preliminary study.Psychiatry Res. 2002; 116: 163-172
- Alcohol-withdrawn animals have a prolonged increase in dopamine D2 high receptors, reversed by general anesthesia: relation to relapse?.Synapse. 2004; 52: 77-83
- Dopamine and N-methyl-D-aspartate receptor expression in peripheral blood of patients undergoing alcohol withdrawal.J Neural Transm. 2007; 114: 1081-1084
- The A9 allele of the dopamine transporter gene is associated with delirium tremens and alcohol-withdrawal seizure.Biol Psychiatry. 2003; 53: 85-92
- Genetics of alcohol withdrawal.Eur Psychiatry. 2000; 15: 135-139
- Overexcitement and disinhibition: dynamic neurotransmitter interactions in alcohol withdrawal.Br J Psychiatry. 1990; 157: 491-499
- The discovery of chlordiazepoxide and the clinical introduction of benzodiazepines: half a century of anxiolytic drugs.J Anxiety Disord. 2011; 25: 554-562
- Medications acting on the GABA system in the treatment of alcoholic patients.Curr Pharm Des. 2010; 16: 2118-2125
- The role of GABAA receptors in the development of alcoholism.Pharmacol Biochem Behav. 2008; 90: 95-104
- GABA-benzodiazepine-barbiturate receptor interactions.J Neurochem. 1981; 37: 1-13
- Benzodiazepines for alcohol withdrawal.Cochrane Database Syst Rev. 2010; ([review]) (CD005063): 1-111
- Pharmacotherapies for alcohol abuse: withdrawal and treatment.Med Clin North Am. 1997; 81: 881-907
- Meta-analysis of benzodiazepine use in the treatment of acute alcohol withdrawal.CMAJ. 1999; 160: 649-679
- New developments for the pharmacological treatment of alcohol withdrawal: A focus on non-benzodiazepine GABAergic medications.Prog Neuropsychopharmacol Biol Psychiatry. 2008; 32: 1106-1117
- Pregabalin, tiapride and lorazepam in alcohol withdrawal syndrome: a multi-centre, randomized single-blind comparison trial.Addiction. 2010; 105: 288-299
- Baclofen for alcohol withdrawal.Cochrane Database Syst Rev. 2011; ([review]) (CD008502): 1-17
- Neurobiology of alcohol.in: Galanter M. Kleber H.D. Textbook of substance abuse treatment. 3rd edition. American Psychiatric Publishing, Washington, DC2004
- Ethanol inhibition of nicotinic acetylcholine type alpha 7 receptors involves the amino-terminal domain of the receptor.Mol Pharmacol. 1996; 50: 1010-1016
- Alcohol modulation of neuronal nicotinic acetylcholine receptors in alpha subunit dependent.Alcohol Clin Exp Res. 2002; 26: 779-784
- Vulnerability factors for alcoholism.in: Davis K.L. Charney D. Coyle J.T. Neuropsychopharmacology: the 5th generation of progress. Lippincott Williams & Wilkins, Philadelphia2002
- Interaction between the serotonin transporter gene variation and rearing condition in alcohol preference and consumption in female primates.Arch Gen Psychiatry. 2004; 61: 1146-1152
- Acid-base and electrolyte abnormalities in alcoholic patients.Miner Electrolyte Metab. 1994; 20: 274-281
- Magnesium deficiency after prolonged parenteral fluid administration and after chronic alcoholism complicated by delirium tremens.J Lab Clin Med. 1954; 43: 169-183
- The role of hypomagnesemia and respiratory alkalosis in the genesis of alcohol-withdrawal symptoms.Ann N Y Acad Sci. 1973; 215: 235-248
- Admission alcohol level: a predictor of the course of alcohol withdrawal.J Fam Pract. 1991; 33: 161-167
- Risk factors for delirium tremens development.J Gen Intern Med. 1996; 11: 410-414
- Independent clinical correlates of severe alcohol withdrawal.Subst Abus. 2003; 24: 197-209
- Parameters affecting the course and results of delirium tremens treatment.Acta Psychiatr Scand Suppl. 1986; s329: 120-123
- The role of somatic disorders and physical injury in the development and course of alcohol withdrawal delirium.Alcohol Clin Exp Res. 1999; 23: 209-213
- The histories of withdrawal convulsions and delirium tremens in 1648 alcohol dependent subjects.Addiction. 1995; 90: 1335-1347
- Benzodiazepine requirements during alcohol withdrawal syndrome: clinical implications of using a standardized withdrawal scale.J Clin Psychopharmacol. 1991; 11: 291-295
- Alcohol withdrawal syndromes: a review of pathophysiology, clinical presentation, and treatment.J Gen Intern Med. 1989; 4: 432-444
- The alcohol withdrawal syndrome.Ann Emerg Med. 1982; 11: 276-280
- Alcohol withdrawal syndrome: alleviating symptoms, preventing progression.J Crit Illn. 1998; 13: 311-317
- Alcohol use disorder and illicit drug use in admissions to general hospitals in the United States.Am J Addict. 2005; 14: 256-267
- Kindling as a model for alcohol withdrawal syndromes.Br J Psychiatry. 1978; 133: 1-14
- Clinical aspects: analysis of the factors determining survival of alcoholic withdrawal syndrome patients in a general hospital.Alcohol Alcohol. 2010; 45: 151-158
- The kindling hypothesis: further evidence from a US national study of alcoholic men.Alcohol Alcohol. 1993; 28: 593-598
- Risk factors for delirium tremens: a retrospective chart review.Am J Addict. 2006; 15: 213-219
- Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse.Pharmacol Ther. 2011; 129: 149-171
- The co-occurrence of alcoholism with other psychiatric disorders in the general population and its impact on treatment.J Stud Alcohol. 1988; 49: 219-224
- Recognition of alcoholism among patients with psychiatric problems in a family practice clinic.J Fam Pract. 1983; 17: 829-832
- Impact of alcohol abuse in the etiology and severity of community-acquired pneumonia.Chest. 2006; 129: 1219-1225
- Alcohol withdrawal.Med Clin North Am. 2001; 85: 1191-1212
- Recognition and management of alcohol withdrawal syndrome.Hosp Pract. 1976; 11: 79-84
- Inappropriate use of symptom-triggered therapy for alcohol withdrawal in the general hospital.Mayo Clin Proc. 2008; 83: 274-279
- Alcohol withdrawal syndrome.in: Kruse J.A. Fink M.P. Carlson R.W. Saunders manual of critical care. Elsevier Science, Philadelphia2003: 240-243
- Alcohol withdrawal syndrome: clinical problems.Snow Tiger Medical Data Base, Houston (TX)1999
- Role of endogenous benzodiazepine ligands and their GABA-A-associated receptors in hepatic encephalopathy.Metab Brain Dis. 2005; 20: 425-437
- Hepatic encephalopathy: from pathophysiology to therapeutic management.Eur J Gastroenterol Hepatol. 2011; 23: 9-22
- Magnesium deficiency in alcohol addiction and withdrawal.Magnes Trace Elem. 1991; 10: 263-268
- Magnesium deficiency in alcoholism.Alcohol Clin Exp Res. 1986; 10: 590-594
- Clinical experience with 781 cases of alcoholism evaluated and treated on an inpatient basis by various methods.Int J Addict. 1985; 20: 643-650
- Association of hypomagnesemia and mortality in acutely ill medical patients.Crit Care Med. 1993; 21: 203-209
- Seizures during detoxification.J Gen Intern Med. 1992; 7: 123
- Placebo-controlled trial of intravenous diphenylhydrantoin for short-term treatment of alcohol withdrawal seizures.Am J Med. 1989; 87: 645-648
- Management of alcohol withdrawal syndromes.Arch Intern Med. 1978; 138: 278-283
- Alcohol-related disorders.in: Sadock B.J. Sadock V.A. Ruiz P. Comprehensive textbook of psychiatry. 9th edition. Lippincott, Philadelphia2009
- A model for predicting alcohol withdrawal delirium.Psychiatr Serv. 2001; 52: 820-823
- A symptom rating scale for delirium.Psychiatry Res. 1988; 23: 89-97
- Intensive care delirium screening checklist: evaluation of a new screening tool.Intensive Care Med. 2001; 27: 859-864
- Delirium in the acute care setting: characteristics, diagnosis and treatment.Crit Care Clin. 2008; 24: 657-722
- Motoric subtypes of delirium.Semin Clin Neuropsychiatry. 2000; 5: 75-85
- The association of the kynurenine pathway of tryptophan metabolism with acute brain dysfunction during critical illness.Crit Care Med. 2012; 40: 835-841
- Delirium as a predictor of long-term cognitive impairment in survivors of critical illness.Crit Care Med. 2010; 38: 1513-1520
- Relationship between symptoms and motoric subtype of delirium.J Neuropsychiatry Clin Neurosci. 2000; 12: 51-56
- Lorazepam is an independent risk factor for transitioning to delirium in intensive care unit patients.Anesthesiology. 2006; 104: 21-26
- Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.JAMA. 2007; 298: 2644-2653
- Benzodiazepine-induced and anticholinergic-induced delirium in the elderly.Int Psychogeriatr. 1991; 3: 397-408
- Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence.J Gerontol A Biol Sci Med Sci. 2008; 63: 764-772
- Cardiorespiratory patterns in severe delirium tremens.Arch Intern Med. 1985; 145: 1057-1059
- Complications of alcohol withdrawal: pathophysiological insights.Alcohol Health Res World. 1998; 22: 61-66
- Severe protracted alcohol withdrawal syndrome: prevalence and pharmacological treatment at an inpatient detoxification unit—a naturalistic study.Pharmacopsychiatry. 2009; 42: 76-78
- Chemotherapy of delirium tremens: a survey of physicians' preferences.Am J Psychiatry. 1974; 131: 1031-1033
- Deficiencies of clinical trials of alcohol withdrawal.Alcohol Clin Exp Res. 1983; 7: 42-44
- Efficacy and safety of pharmacological interventions for the treatment of the alcohol withdrawal syndrome.Cochrane Database Syst Rev. 2011; 15: 1-25
- Comparative evaluation of treatments of alcohol withdrawal syndromes.JAMA. 1967; 201: 99-102
- Diazepam loading: simplified treatment of alcohol withdrawal.Clin Pharmacol Ther. 1983; 34: 822-826
- Alcohol withdrawal pharmacotherapy for inpatients with medical comorbidity.J Addict Dis. 2006; 25: 17-24
- Symptom-triggered vs fixed-schedule doses of benzodiazepine for alcohol withdrawal: a randomized treatment trial.Arch Intern Med. 2002; 162: 1117-1121
- Individualized treatment for alcohol withdrawal.JAMA. 1994; 272: 519-523
- Alcohol withdrawal: what is the benzodiazepine of choice?.Ann Pharmacother. 1994; 28: 67-71
- A double-blind comparison of the efficacy and safety of lorazepam and diazepam in the treatment of the acute alcohol withdrawal syndrome.Clin Ther. 1984; 6: 364-371
- Comparison of two benzodiazepines in the treatment of alcohol withdrawal: effects on symptoms and cognitive recovery.Drug Alcohol Depend. 1986; 18: 329-334
- Double-blind comparison of lorazepam and chlordiazepoxide in the treatment of the acute alcohol abstinence syndrome.Clin Ther. 1983; 6: 52-58
- Diazepam pharmacokinetics after intravenous administration in alcohol withdrawal.Br J Clin Pharmacol. 1983; 15: 125-127
- Pharmacokinetics of midazolam administered by continuous intravenous infusion to intensive care patients.Crit Care Med. 1992; 20: 1123-1126
- Dexmedetomidine vs midazolam for sedation of critically ill patients.JAMA. 2009; 301: 489-499
- The use of continuous IV sedation is associated with prolongation of mechanical ventilation.Chest. 1998; 114: 541-548
- New agents for sedation in the intensive care unit.Crit Care Clin. 2001; 17: 881-897
- Alcohol withdrawal severity is decreased by symptom-oriented adjusted bolus therapy in the ICU.Intensive Care Med. 2003; 29: 2230-2238
- Routine hospital alcohol detoxification practice compared to symptom triggered management with an objective withdrawal scale (CIWA-Ar).Am J Addict. 2009; 9: 135-144
- Impact of severe delirium tremens (DT) on postoperative-traumatic recovery with the application of the CIWA-Ar.Crit Care Med. 2010; 38: 793
- High-dose intravenous benzodiazepine.Acad Emerg Med. 2000; 7: 308-310
- Resistant alcohol withdrawal: does an unexpectedly large sedative requirement identify these patients early?.J Med Toxicol. 2006; 2: 55-60
- Unprecedented sedative requirements during delirium tremens.Crit Care Med. 1985; 13: 246-247
- Prolonged delirium tremens requiring massive doses of medication.J Am Board Fam Pract. 1993; 6: 502-504
- Massive benzodiazepine requirements during alcohol withdrawal.Am J Psychiatry. 1979; 136: 821-823
- Effect of ethanol administration and withdrawal on benzodiazepine receptor binding in the rat brain.Neuropharmacology. 1982; 21: 283-286
- Chronic ethanol administration alters gamma-aminobutyric acid, pentobarbital and ethanol-mediated 36Cl-uptake in cerebral cortical synaptoneurosomes.J Pharmacol Exp Ther. 1988; 246: 158-164
- Benzodiazepines in the treatment of alcoholism.Recent Dev Alcohol. 1989; 7: 283-313
- Propofol: therapeutic indications and side-effects.Curr Pharm Des. 2004; 10: 3639-3649
- The pathophysiology of the propofol infusion syndrome: a simple name for a complex syndrome.Intensive Care Med. 2003; 29: 1417-1425
- Refractory delirium tremens: a case series.Crit Care Med. 2000; 28: 1781-1784
- Successful use of propofol in refractory delirium tremens.Ann Emerg Med. 1997; 30: 825-828
- Strategies for managing delirium tremens in the ICU.J Crit Illn. 1997; 12: 140-149
- Dexmedetomidine infusion as adjunctive therapy to benzodiazepines for acute alcohol withdrawal.Ann Pharmacother. 2008; 42: 1703-1705
- Dexmedetomidine.Curr Opin Crit Care. 2001; 7: 221-226
- Phenobarbital versus diazepam for delirium tremens—a retrospective study.Dan Med Bull. 2010; 57: A4169
- Baclofen in the treatment of alcohol withdrawal syndrome: a comparative study vs diazepam.Am J Med. 2006; 119: 276.e13-276.e18
- Gamma-hydroxybutyric acid versus clomethiazole for the treatment of alcohol withdrawal syndrome in a medical intensive care unit: an open, single-center randomized study.Am J Drug Alcohol Abuse. 2009; 35: 189-192
- A double-blind trial of gabapentin versus lorazepam in the treatment of alcohol withdrawal.Alcohol Clin Exp Res. 2009; 33: 1582-1588
- An overview of medications for treatment of alcohol withdrawal and alcohol dependence with an emphasis on the use of older and newer anticonvulsants.Addict Behav. 2006; 31: 1628-1649
- Divalproex sodium (Depakote) for alcohol withdrawal and relapse prevention.J Addict Dis. 2002; 21: 55-64
- Update on anticonvulsants for the treatment of alcohol withdrawal.Am J Addict. 2001; 10: 116-123
- Management of the alcohol withdrawal syndrome.Annu Rev Med. 1991; 42: 323-340
- Diphenylhydantoin control of alcohol withdrawal seizures.JAMA. 1974; 230: 1430-1432
- The lack of efficacy of phenytoin in the prevention of recurrent alcohol-related seizures.Ann Emerg Med. 1994; 23: 513-518
- Propranolol associated confused states during alcohol withdrawal.J Clin Psychopharmacol. 1983; 3: 185-187
- Efficacy of clonidine in treatment of alcohol withdrawal state.Psychopharmacology. 1983; 81: 78-80
- Is clonidine useful in the treatment of alcohol withdrawal?.Alcohol Clin Exp Res. 1989; 13: 95-98
- Control of acute alcoholic withdrawal symptoms: a comparative study of haloperidol and chlordiazepoxide.Curr Ther Res Clin Exp. 1976; 20: 289-299
- Enhancement of alcohol-withdrawal convulsions in mice by haloperidol.Clin Toxicol. 1976; 9: 427-434
- Effect of memantine on cue-induced alcohol craving in recovering alcohol-dependent patients.Am J Psychiatry. 2007; 164: 519-523
- The CAGE questionnaire: validation of a new alcoholism screening instrument.Am J Psychiatry. 1974; 131: 1121-1123
- Administration of intravenous alcohol for prevention of withdrawal in alcoholic burn patients.Am J Surg. 1984; 148: 266-269
- Intravenous ethanol for alcohol detoxification in trauma patients.South Med J. 1994; 87: 47-54
- Alcohol prescription by surgeons in the prevention and treatment of delirium tremens: historic and current practice.Gen Hosp Psychiatry. 2002; 24: 257-259
- Massive doses of midazolam infusion for delirium tremens.Crit Care Med. 1989; 17: 597
- An ethanol protocol to prevent alcohol withdrawal syndrome.J Am Coll Surg. 2006; 203: 186-191
- Comparison of intravenous ethanol versus diazepam for alcohol withdrawal prophylaxis in the trauma ICU: results of a randomized trial.J Trauma. 2008; 64: 99-104
- Standard calculation of ethanol elimination rate is not sufficient to provide ethanol substitution therapy in the postoperative course of alcohol-dependent patients.Intensive Care Med. 1998; 24: 459-463
- Blood alcohol concentration for monitoring ethanol treatment to prevent alcohol withdrawal in the intensive care unit.Intensive Care Med. 2002; 28: 1475-1482
- Intravenous ethanol for the treatment of alcohol withdrawal syndrome in critically ill patients.Pharmacotherapy. 2004; 24: 1578-1585
- Ethanol for the treatment of alcohol withdrawal symptoms: a questionable approach.Neurologist. 2010; 16: 211
- Ethanol.in: Brunton L.L. Lazo J.S. Parker K.L. Goodman & Gillman's the pharmacological basis of therapeutics. 11th edition. McGraw Hill, New York2006: 591-601
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