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Research Article| Volume 7, ISSUE 3, P615-637, July 1991

Opioids and Other Analgesics

Adverse Effects in the Intensive Care Unit
  • Author Footnotes
    * Pediatric Clinical Pharmacy Specialist
    Marcia L. Buck
    Correspondence
    Address reprint requests to: Marcia L. Buck, PharmD University of Virginia, Children’s Medical Center, Box 274, Charlottesville, VA 22908
    Footnotes
    * Pediatric Clinical Pharmacy Specialist
    Affiliations
    From the University of Virginia, Children's Medical Center, Charlottesvill, Virginia
    Search for articles by this author
  • Author Footnotes
    † Chief, Division of Pharmacology and Critical Cars
    Jeffrey L. Blumer
    Footnotes
    † Chief, Division of Pharmacology and Critical Cars
    Affiliations
    From the University of Virginia, Children's Medical Center, Charlottesvill, Virginia
    Search for articles by this author
  • Author Footnotes
    * Pediatric Clinical Pharmacy Specialist
    † Chief, Division of Pharmacology and Critical Cars
DOI:https://doi.org/10.1016/S0749-0704(18)30298-7
Opioids and Other Analgesics
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      Medications for pain relief are an important component of therapy for intensive care patients. Opioids, the most commonly used analgesics in the ICLJ setting, are associated with a large number of adverse effects that are related to their binding properties at opioid-receptor subtypes. Other analgesics, such as ketamine and nonsteroidal anti-inflammatory agents, may cause fewer cardiovascular and respiratory effects, but lead to other unwanted effects in ICU patients. In addition to a review of analgesic-associated adverse effects and drug interactions, guidelines for anticipating and monitoring these agents are presented.
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      DOI: https://doi.org/10.1016/S0749-0704(18)30298-7

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      © 1991 Elsevier Inc. Published by Elsevier Inc. All rights reserved.

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