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Research Article| Volume 7, ISSUE 3, P659-693, July 1991

Toxic Effects of Electrolyte and Trace Mineral Administration in the Intensive Care Unit

  • James B. Besunder
    Correspondence
    Address reprint requests to: James B. Besunder, DO, Pediatric Critical Care and Pharmacology, Department of Pediatrics, MetroHealth Medical Center, 3395 Scranton Road, Cleveland, OH 44109
    Affiliations
    Assistant Professor of Pediatrics, Case Western Reserve University, School of Medicine; and Director, Pediatric Critical Care and Pharmacology, Department of Pediatrics, MetroHealth Medical Center, Cleveland, Ohio
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  • Paul G. Smith
    Affiliations
    Senior Instructor of Pediatrics, Case Western Reserve University, School of Medicine; and Divisions of Pediatric Critical Care and Pediatric Pulmonology, Rainbow Babies and Children’s Hospital, Cleveland, Ohio
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      This paper is only available as a PDF. To read, Please Download here.
      Recent studies have expanded our knowledge of the diverse physiologic roles of sodium, potassium, chloride, calcium, magnesium, and phosphorous. Their roles are not limited to passive fluid and electrochemical regulation. This article reviews the physiologic function and indications for these electrolytes and trace minerals and discusses toxicities associated with their use. Dosing guidelines and recommendations for monitoring are outlined to maximize efficacy and minimize adverse effects.
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