This paper is only available as a PDF. To read, Please Download here.
The hypermetabolism-organ failure complex is a systemic metabolic disorder. Reductions
in morbidity and mortality require the restoration and maintenance of oxygen transport
and the rise of metabolic support. Metabolic support requires an understanding of
the metabolic response to injury and the principles of basic nutrition. When knowledgeably
applied, metabolic support is safe and effective.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribers receive full online access to your subscription and archive of back issues up to and including 2002.
Content published before 2002 is available via pay-per-view purchase only.
Subscribe:
Subscribe to Critical Care ClinicsAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Nutrition and the respiratory system.Crit. Care Med. 1982; 10: 162
- Respiratory changes induced by the large glucose loads of total parenteral nutrition.J.A.M.A. 1980; 243: 1444
- Stimulation of muscle protein degradation and prostaglandin E2 release by leukocyte pyrogen: A mechanism for the increased degradation of muscle proteins during fever.N. Engl. J. Med. 1983; 308: 553-558
- Gluconeogenesis, ureagenesis andketogenesis during sepsis.J.P.E.N. 1980; 4: 277-285
- Branched chain amino acid administration and metabolism during starvation, injury and infection.Surgery. 1979; 86: 307
- Pocket Manual of Surgical Nutrition.C.V. Mosby Co., St. Louis1984
- Branched chain metabolic support: A prospective, randomized, double-blind trial.Ann. Surg. 1984; 199: 286-291
- Nitrogen retention in critically ill patients is proportional to the branched chain load.Crit. Care Med. 1983; 11: 775
- Enteral feeding in sepsis: A prospective, randomized, double blind trial.Surgery. 1985; 98: 632-639
- Correlations between metabolic and cardiopulmonary measurements in patients after trauma, general surgery, and sepsis.J. Trauma. 1979; 19: 621-629
- The hepatic failure of sepsis: Cellular versus substrate.Surgery. 1979; 86: 409-422
- Septic autocannibalism: A failure of exogenous nutritional support.Ann. Surg. 1980; 192: 570-580
- Branched chains support postoperative protein synthesis.Surgery. 1982; 92: 192-199
- Endogenous and exogenous catecholamines in critical care medicine.Crit. Care Med. 1982; 10: 409-416
- Muscle proteolysis induced by a circulating peptide in patients with sepsis or trauma.N. Engl. J. Med. 1983; 308: 545-552
- Refeeding syndrome: Transient elevation of serum liver enzymes following resumption of gut feedings in patients receiving total parenteral nutrition.Surg. Forum. 1984; 35: 79-82
- Alterations in amino acid clearance during ischemia predicts hepatocellular ATP changes.Surgery. 1985; 98: 396-404
- Multiple systems organ failure: Mechanisms and therapy.Surg. Annu. 1982; 14: 27-72
- Anaphylatoxin generation in multiple systems organ failure.J. Trauma. 1984; 24: 1038
- The main determinants of nitrogen balance during total parenteral nutrition in critically ill injured patients.Intensive Care Med. 1984; 10: 251-254
- The Biology of Human Starvation.University of Minnesota Press, Minneapolis1950
- The effect of injury on metabolism.Br. J. Surg. 1967; 54: 435
- Oxygen tension regulates the expression of angiogenesis factor by macrophages.Science. 1983; 221: 1283
- Muscle protein catabolism in the septic patient as measured by 3-methylhistidine excretion.Am. J. Clin. Nutr. 1977; 30: 1349-1352
- Prolonged intensive care: Worth the price?.Arch. Surg. 1985; 120: 698-702
- Substrate composition and sepsis.Arch. Surg. 1983; 118: 176
- Lymphokines: Their role in lymphocyte responses. Properties of interleukin I.Fed. Proc. 1982; 41: 257-262
- Arachidonic acid, prostaglandin E2 and F2 influence rates of protein turnover in skeletal and cardiac muscle.J. Biol. Chem. 1982; 257: 1632-1638
- Physiological and metabolic correlations in human, sepsis.Surgery. 1979; 86: 163
- Amino acids and respiration.Ann. Intern. Med. 1983; 98: 41
- Effect of injury and infection on visceral metabolism and circulation.Ann. Surg. 1980; 192: 491
- Impaired glucose flow in burned patients with gram-negative sepsis.Surg. Gynecol. Obstet. 1976; 143: 720-724
Article info
Footnotes
Supported by grant no. 1R01-HL 31045-01, from the National Heart and Lung Institute.
Identification
Copyright
© 1986 Elsevier Inc. Published by Elsevier Inc. All rights reserved.