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Neuroprognostication

  • Victoria Fleming
    Affiliations
    Department of Neurology, University of Massachusetts Chan Medical School, 55 Lake Avenue North, S-5, Worcester, MA 01655, USA
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  • Susanne Muehlschlegel
    Correspondence
    Corresponding author.
    Affiliations
    Department of Neurology, University of Massachusetts Chan Medical School, 55 Lake Avenue North, S-5, Worcester, MA 01655, USA

    Department of Anesthesiology/Critical Care, University of Massachusetts Chan Medical School, 55 Lake Avenue North, S-5, Worcester, MA 01655, USA

    Department of Surgery, University of Massachusetts Chan Medical School, 55 Lake Avenue North, S-5, Worcester, MA 01655, USA
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Published:October 13, 2022DOI:https://doi.org/10.1016/j.ccc.2022.06.005

      Keywords

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      References

      1. Prognosis Definition & meaning - Merriam-Webster.
        (Available at:) (Accessed January 18, 2022)
        • Feigin V.L.
        • Vos T.
        • Nichols E.
        • et al.
        The global burden of neurological disorders: translating evidence into policy.
        Lancet Neurol. 2020; 19: 255-265
        • Hwang D.Y.
        • Chu S.Y.
        • Dell C.A.
        • et al.
        Factors considered by clinicians when prognosticating intracerebral hemorrhage outcomes.
        Neurocrit Care. 2017; 27: 316-325
        • Steinberg A.
        • Grayek E.
        • Arnold R.M.
        • et al.
        Physicians’ cognitive approach to prognostication after cardiac arrest.
        Resuscitation. 2022; https://doi.org/10.1016/J.RESUSCITATION.2022.01.001
      2. Ge C, Goss AL, Crawford S, et al. Variability of Prognostic Communication in Critically Ill Neurologic Patients: A Pilot Multicenter Mixed-Methods Study. Crit Care Explor 2022;4:e0640

        • Rabinstein A.A.
        • Hemphill J.C.
        Prognosticating after severe acute brain disease: science, art, and biases.
        Neurology. 2010; 74: 1086-1087
        • Gao M.M.
        • Wang J.
        • Saposnik G.
        The art and science of stroke outcome prognostication.
        Stroke. 2020; : 1358-1360
        • Maciel C.B.
        Neurologic outcome prediction in the intensive care Unit.
        Continuum (Minneapolis, Minn). 2021; 27: 1405-1429
        • Fidali B.C.
        • Stevens R.D.
        • Claassen J.
        Novel approaches to prediction in severe brain injury.
        Curr Opin Neurol. 2020; 33: 669
        • Johnston S.C.
        Prognostication matters.
        Muscle & Nerve. 2000; 23: 839-842
        • Giacino J.T.
        • Katz D.I.
        • Schiff N.D.
        • et al.
        Practice guideline update recommendations summary: disorders of consciousness: report of the guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of neurology; the American Congress of Rehabilitation medicine; and the national Institute on disability, Independent living, and Rehabilitation research.
        Neurology. 2018; 91: 450
        • Geocadin R.G.
        • Callaway C.W.
        • Fink E.L.
        • et al.
        Standards for studies of neurological prognostication in comatose survivors of cardiac arrest: a scientific statement from the American Heart association.
        Circulation. 2019; 140: E517-E542
        • Muehlschlegel S.
        • Wartenberg K.
        • Alexander S.
        • et al.
        Neuroprognostication guideline - a collaboration of neurocritical care society (NCS)and Deutsche Gesellschaft fuer Neurointensivmedizin (DGNI).
        ANIM. 2022;
      3. Kahneman D. Thinking, Fast and Slow. Farrar, Straus and Giroux; 2011.

        • Mohan D.
        • Farris C.
        • Fischhoff B.
        • et al.
        Efficacy of educational video game versus traditional educational apps at improving physician decision making in trauma triage: randomized controlled trial.
        BMJ. 2017; 359
        • Tversky A.
        • Kahneman D.
        Judgment under uncertainty: heuristics and biases.
        Science. 1974; 185: 1124-1131
        • Marewski J.N.
        • Gigerenzer G.
        Heuristic decision making in medicine.
        Dialogues Clin Neurosci. 2012; 14: 77
        • Saposnik G.
        • Redelmeier D.
        • Ruff C.C.
        • et al.
        Cognitive biases associated with medical decisions: a systematic review.
        BMC Med Inform Decis Making. 2016; 16: 1-14
        • Becker K.J.
        • Baxter A.B.
        • Cohen W.A.
        • et al.
        Withdrawal of support in intracerebral hemorrhage may lead to self-fulfilling prophecies.
        Neurology. 2001; 56: 766-772
        • Turgeon A.F.
        • Lauzier F.
        • Simard J.F.
        • et al.
        Mortality associated with withdrawal of life-sustaining therapy for patients with severe traumatic brain injury: a Canadian multicentre cohort study.
        CMAJ. 2011; 183: 1581-1588
        • Creutzfeldt C.J.
        • Longstreth W.T.
        • Holloway R.G.
        Predicting decline and survival in severe acute brain injury: the fourth trajectory.
        BMJ (Clinical research ed). 2015; : 351https://doi.org/10.1136/BMJ.H3904
        • Hemphill J.C.
        • White D.B.
        Clinical nihilism in Neuroemergencies.
        Emerg Med Clin North America. 2009; 27: 27-37
        • Williamson T.
        • Ryser M.D.
        • Ubel P.A.
        • et al.
        Withdrawal of life-supporting treatment in severe traumatic brain injury.
        JAMA Surg. 2020; 155: 723
        • Holloway R.G.
        • Benesch C.G.
        • Burgin W.S.
        • et al.
        Prognosis and decision making in severe stroke.
        JAMA. 2005; 294: 725-733
        • Graham M.
        Burying our mistakes: Dealing with prognostic uncertainty after severe brain injury.
        Bioethics. 2020; 34: 612
        • Zahuranec D.B.
        • Fagerlin A.
        • Sánchez B.N.
        • et al.
        Variability in physician prognosis and recommendations after intracerebral hemorrhage.
        Neurology. 2016; 86: 1864
        • Hirschi R.
        • Rommel C.
        • Hawryluk G.W.J.
        Should we have a guard against therapeutic nihilism for patients with severe traumatic brain injury?.
        Neural Regen Res. 2017; 12: 1801
        • Moore N.A.
        • Brennan P.M.
        • Baillie J.K.
        Wide variation and systematic bias in expert clinicians’ perceptions of prognosis following brain injury.
        Br J Neurosurg. 2013; 27: 340-343
        • Geocadin R.G.
        • Peberdy M.A.
        • Lazar R.M.
        Poor survival after cardiac arrest resuscitation: a self-fulfilling prophecy or biologic destiny?.
        Crit Care Med. 2012; 40: 979-980
      4. Izzy S, Compton R, Carandang R, Hall W, Muehlschlegel S. Self-fulfilling prophecies through withdrawal of care: do they exist in traumatic brain injury, too? Neurocrit Care 2013;19:347-63.

        • Souter M.J.
        • Blissitt P.A.
        • Blosser S.
        • et al.
        Recommendations for the critical care management of devastating brain injury: prognostication, Psychosocial, and ethical management: a Position statement for Healthcare Professionals from the neurocritical care society.
        Neurocrit Care. 2015; 23: 4-13
        • Lee D.H.
        • Cho Y.S.
        • Lee B.K.
        • et al.
        Late awakening is common in settings without withdrawal of life-sustaining therapy in out-of-hospital cardiac arrest survivors who Undergo Targeted temperature management.
        Crit Care Med. 2022; 50: 235-244
        • Schenker Y.
        • White D.B.
        • Crowley-Matoka M.
        • et al.
        It Hurts to Know and it helps”: Exploring how surrogates in the ICU Cope with prognostic information.
        J. Palliat Med. 2013; 16 (Available at:): 243-249
        • Quinn T.
        • Moskowitz J.
        • Khan M.W.
        • et al.
        What families need and physicians deliver: Contrasting communication preferences between surrogate decision-makers and physicians during outcome prognostication in critically ill TBI patients.
        Neurocrit Care. 2017; 27: 154-162
        • Zier L.S.
        • Burack J.H.
        • Micco G.
        • et al.
        Doubt and belief in physicians’ ability to prognosticate during critical illness: the perspective of surrogate decision makers.
        Crit Care Med. 2008; 36: 2341
        • Boyd E.A.
        • Lo B.
        • Evans L.R.
        • et al.
        It’s not just what the doctor tells me:” Factors that influence surrogate decision-makers’ perceptions of prognosis.
        Crit Care Med. 2010; 38: 1270
        • Moskowitz J.
        • Quinn T.
        • Khan M.W.
        • et al.
        Should We Use the IMPACT-model for the outcome prognostication of TBI patients? A qualitative study assessing physicians’ perceptions.
        MDM Pol Pract. 2018; 3 (2381468318757987)
        • Creutzfeldt C.J.
        • Holloway R.G.
        • Curtis J.R.
        Palliative care: a Core Competency for stroke Neurologists.
        Stroke. 2015; 46: 2714-2719
        • Christakis N.A.
        • Iwashyna T.J.
        Attitude and self-reported practice regarding prognostication in a national sample of internists.
        Arch Intern Med. 1998; 158: 2389-2395
        • White D.B.
        • Engelberg R.A.
        • Wenrich M.D.
        • et al.
        The language of prognostication in intensive care Units.
        Med Decis making : Int J Soc Med Decis Making. 2010; 30: 76
        • Apatira L.
        • Boyd E.A.
        • Malvar G.
        • et al.
        Hope, Truth, and preparing for death: Perspectives of surrogate decision makers.
        Ann Intern Med. 2008; 149: 861
      5. Muehlschlegel S, Perman SM, Elmer J, et al. The Experiences and Needs of Families of Comatose Patients After Cardiac Arrest and Severe Neurotrauma: The Perspectives of National Key Stakeholders During a National Institutes of Health-Funded Workshop. Crit Care Explor 2022;4:e0648

        • Jones K.
        • Quinn T.
        • Mazor K.M.
        • et al.
        Prognostic uncertainty in critically ill patients with traumatic brain injury: a Multicenter qualitative study.
        Neurocrit Care. 2021; 35: 311-321
        • Evans L.R.
        • Boyd E.A.
        • Malvar G.
        • et al.
        Surrogate decision-makers’ Perspectives on discussing prognosis in the Face of uncertainty.
        Am J Respir Crit Care Med. 2009; 179: 48
        • Smith A.K.
        • White D.B.
        • Arnold R.M.
        Uncertainty: the other side of prognosis.
        N Engl J Med. 2013; 368: 2448
        • Lazaridis C.
        Withdrawal of life-sustaining treatments in Perceived devastating brain injury: the Key role of uncertainty.
        Neurocrit Care. 2019; 30: 33-41
        • Smith A.K.
        • Williams B.A.
        • Lo B.
        Discussing overall prognosis with the very Elderly.
        N Engl J Med. 2011; 365: 2149
        • Schutz R.E.C.
        • Coats H.L.
        • Engelberg R.A.
        • et al.
        Is there hope? Is She there? How families and clinicians experience severe acute brain injury.
        J Palliat Med. 2017; 20: 170-176
        • Zier L.S.
        • Sottile P.D.
        • Hong S.Y.
        • et al.
        Surrogate decision makers’ interpretation of prognostic information: a mixed-methods study.
        Ann Intern Med. 2012; 156: 360-366
        • Quill T.E.
        • Holloway R.
        Time-limited trials near the end of life.
        JAMA - J Am Med Assoc. 2011; 306: 1483-1484
        • Hemphill J.C.
        • Farrant M.
        • Neill T.A.
        Prospective validation of the ICH Score for 12-month functional outcome.
        Neurology. 2009; 73: 1088
        • Hwang D.Y.
        • Dell C.A.
        • Sparks M.J.
        • et al.
        Clinician judgment vs formal scales for predicting intracerebral hemorrhage outcomes.
        Neurology. 2016; 86: 126-133
        • Dijkland S.A.
        • Foks K.A.
        • Polinder S.
        • et al.
        Prognosis in moderate and severe traumatic brain injury: a systematic review of contemporary models and validation studies.
        J Neurotrauma. 2020; 37: 1-13
        • Pochard F.
        • Azoulay E.
        • Chevret S.
        • et al.
        Symptoms of anxiety and depression in family members of intensive care unit patients: ethical hypothesis regarding decision-making capacity.
        Crit Care Med. 2001; 29: 1893-1897
        • Curtis J.R.
        • Engelberg R.A.
        • Wenrich M.D.
        • et al.
        Missed Opportunities during family conferences about end-of-life care in the intensive care Unit.
        Am J Respir Crit Care Med. 2012; 171: 844-849
        • Azoulay E.
        • Chevret S.
        • Leleu G.
        • et al.
        Half the families of intensive care unit patients experience inadequate communication with physicians.
        Crit Care Med. 2000; 28 (Available at:)
        • Wendler D.
        • Rid A.
        Systematic review: the effect on surrogates of making treatment decisions for others.
        Ann Intern Med. 2011; 154: 336-346
        • Gay E.B.
        • Pronovost P.J.
        • Bassett R.D.
        • et al.
        The intensive care unit family meeting: making it happen.
        J Crit Care. 2009; 24: 629.e1
        • Kon A.A.
        • Davidson J.E.
        • Morrison W.
        • et al.
        Shared decision making in intensive care Units: an American College of critical care medicine and American Thoracic society policy statement.
        Crit Care Med. 2016; 44: 188
        • Azoulay E.
        The end-of-life family conference.
        Am J Respir Crit Care Med. 2012; 171: 803-804
        • Khan M.W.
        • Muehlschlegel S.
        Shared decision-making in neurocritical care.
        Neurol Clin. 2017; 35: 825
        • Heyland D.K.
        • Heyland R.
        • Dodek P.
        • et al.
        Discordance between patients’ stated values and treatment preferences for end-of-life care: results of a multicentre survey.
        BMJ Support Palliat Care. 2017; 7: 292-299
        • Bouniols N.
        • Leclère B.
        • Moret L.
        Evaluating the quality of shared decision making during the patient-carer encounter: a systematic review of tools.
        BMC Res Notes. 2016; 9https://doi.org/10.1186/S13104-016-2164-6
        • White D.B.
        • Engelberg R.A.
        • Wenrich M.D.
        • et al.
        Prognostication during physician-family discussions about limiting life support in intensive care units.
        Crit Care Med. 2007; 35: 442-448
        • White D.B.
        • Braddock C.H.
        • Bereknyei S.
        • et al.
        Toward shared decision making at the end of life in intensive care Units: Opportunities for Improvement.
        Arch Intern Med. 2007; 167: 461-467
        • White D.B.
        • Malvar G.
        • Karr J.
        • et al.
        Expanding the paradigm of the physician’s role in surrogate decision-making: an empirically derived framework.
        Crit Care Med. 2010; 38: 743-750